A large portion of the cannabis plant’s therapeutic potential remains largely untapped due to prohibition. However, as cannabis becomes more legitimized, researchers have begun to find new and exciting uses for many of the plant’s unique compounds.
CBC has been shown to reduce intraocular pressure in rabbits and have anti-inflammatory and neuroprotective effects. It also enhances the effects of other cannabinoids, contributing to the entourage effect.
Anxiolytic
Despite being around for more than 50 years, CBT cannabinoid has received relatively little research or media attention. Nonetheless, it is a potent anxiolytic that can inhibit THC’s psychotropic effects.
A recent study showed that ICART was as effective as MET-CBT for treating anxiety disorders in cannabis users. The study also found that ICART produced similar decreases in cannabis use as MET-CBT. In addition, researchers discovered that CBT is an estrogen receptor antagonist, which may be helpful in the prevention of breast cancer.
Antidepressant
Although it has a similar molecular structure to THC, CBT does not have psychoactive effects. It is often mixed with CBD or other non-psychoactive hemp cannabinoids in products like tinctures and oils for vaporizer consumption.
Frontline treatments for anxiety disorders include cognitive behavioral therapy and medications that increase serotonin levels. However, these drugs do not work for everyone.
Chronic treatment with antidepressants increases the expression of CB1 receptors and endocannabinoid content in brain regions that regulate mood and anxiety. It also enhances adult hippocampal neurogenesis, which is believed to play a role in antidepressant action.
Antipsychotic
Cannabis may have antipsychotic properties, and CBD is one of the cannabinoids with the potential to help improve schizophrenic symptoms. Its low psychoactivity makes it a safer alternative to high-potency CB1 agonists. Research also suggests that dronabinol can reduce the reinstatement of fear responses in preclinical PTSD models.
This minor cannabinoid is found in small quantities in only a few cannabis strains. It has a molecular structure similar to THC but no psychoactive effects. It is often found in hemp products alongside other cannabinoids like CBD and CBG.
Neuroprotective
CBT is a cannabinoid that has not enjoyed the same popularity as CBD or THC but is slowly catching up. The compound is usually found in products like tinctures, oils, and extracts.
It has been shown to inhibit lipid peroxidation and reduce ROS production, which can damage cells. It also has estrogen receptor-modulating properties, which could be used to treat breast cancer.
Researchers are attempting to find out more about the effects of CBT. They have already discovered that it has some antidepressant effects and can help prevent mania in bipolar disorder patients.
Antioxidant
CBD is a naturally occurring cannabinoid that has not been the focus of many studies, but it is likely to gain attention as more people become aware of its non-intoxicating effects. It may even work with CBG, boosting the energy-boosting and focus-enhancing properties of the latter cannabinoid.
One study found that CBD counteracts UV-induced modifications of lipids and proteins in skin keratinocytes by inhibiting 4-HNE formation, decreasing carbonyl groups, and blocking the PI3K/AKT/mTOR pathway. CBD also increases PPARg activity, which promotes anti-inflammatory and antioxidant actions.
Anti-Inflammatory
CBD is an effective anti-inflammatory and has been shown to reduce oxidative stress. It has also been shown to inhibit the production of proinflammatory cytokines by modulating G-protein coupled receptors.
Studies in CB1-deficient mice have shown that the endocannabinoid system dampens colonic inflammation by suppressing the production of proinflammatory cytokines and enhancing the release of anti-inflammatory cytokines.
It is also able to stimulate vanilloid receptors, which results in desensitization of the pain receptors and paradoxical analgesia.
Anti-Infective
CBT is an anti-inflammatory and has anti-emetic properties. It is also an estrogen receptor agonist. Studies have shown it can significantly reduce chemotherapy-induced nausea and vomiting in mice.
It has similar molecular structures to THC but is less psychoactive. CBT is not found in all cannabis strains and is not very well known.
CBT is a non-intoxicating cannabinoid, like its parent compound, CBC (cannabigerol). Both are non-psychoactive and are formed via enzymatic processes in the plant.
Anti-Obesity
CBT is one of the minor cannabinoids found in cannabis. It has a molecular structure identical to THC and CBD but differs in two ways.
This compound has been claimed to promote weight loss by stimulating the CB1 receptors, which reduce appetite. It is also claimed to convert white fat cells into brown fat, which burns calories.
CBD has also been shown to promote wakefulness in rats and thus could be developed for treating sleep disorders such as narcolepsy. There is limited preclinical and clinical evidence of its effectiveness, however.
Anti-Aging
The anti-aging potential of CBD is a bit of a mystery. It helps keep bones strong by reducing inflammation and encouraging cell repair.
Its hydrating properties can improve skin elasticity and reduce wrinkles while balancing sebum production can prevent oily skin and acne. CBD has also been shown to inhibit mTOR, a key regulator of fundamental cellular processes associated with aging.
It has been shown to lower intraocular pressure, so it could potentially treat glaucoma. Finding pure CBG products is scarce, but you can get it in tinctures and oils.
